Carbon emission reduction of manufacturing industry is related to green development and ecological civilization construction. Based on the inherent requirement of manufacturing high quality development, the use of 2009-2018 data of 27 niche manufacturing industry of our country, in measuring the manufacturing technology progress deviation index and carbon emissions, based on the regression model and GMM dynamic panel model, the influence of FDI introduction, technological progress bias and carbon emissions is demonstrated empirically.The research finds that the technology spillover effect and technology progress bias introduced by FDI affect the carbon emission of the manufacturing industry. The overall impact of FDI introduction on China’s manufacturing carbon emissions is negatively correlated. Capital-intensive manufacturing industry compared with manufacturing industry as a whole, the interaction of FDI and technological progress bias with carbon emissions is significantly related to the accumulation effect shows that FDI technological progress direction is to further deepen the degree of capital, and the interaction coefficient of labor-intensive industry is not significant; In terms of R&D input, the overall manufacturing industry, capital-intensive industries and labor-intensive industries are positively correlated with carbon emissions in the sample period, and the increase of R&D in labor-intensive industries promotes more carbon emissions. Finally, the corresponding policy suggestions are put forward.