The cooperative innovation of industry,university and research instit ute is an effective pattern of technological innovation and an important course for enterprise to take in order build core competence.Independent intellectual p roperty is a protective screen of the enterprises that are competing in the worl d market and can raise the cooperative innovation of industry,university and res earch institute to a higher level in essence.Since independent intellectual prop erty protects the achievement made through the cooperative innovation it will ma ke the enterprise more competitive.This paper details the relations between coop erative innovation of industry,university and research institute and independent intellectual property through analyzing the course of cooperative innovation an d related factors.A core technological system centering independent intellectual property through the process of cooperative innovation of industry,university a nd research institute is established to raise the competitiveness of industries.