To obtain spillovers is one of the key criteria of appraising the performance of attracting FDI and adjust FDI policy for the government of host country.Using provincial data from 1991-2002,this paper investigates the spillover effect of foreign direct investment(FDI) on the domestic science and technical(S&T) innovation activity in China,and analyzes the main factor that affects spillover effect.The empirical study finds that FDI has positive promoting effects on the domestic S&T advancement by improving intramural expenditure-output productivity of S&T development.In general,the average marginal coefficient of FDI spillover effects keep on increasing as time goes by.The marginal spillovers of FDI are uneven among regions,mainly for the reason of difference between macro and micro absorptive climate.