The central region development is crucial for the overall situation of national development. Currently, the development of the central region faces new opportunities under the guidance of scientific concept of development. Relying on independent innovation, improving restructuring and promoting the change of economic growth mode are crucial for the central region to energize. Focusing on promoting independence innovation ability, we must establish and complete regional innovation system, significantly promote the integrated innovation ability and competitiveness of the central region to realize its energizing.