Based on the literature review of Karasek's job demands-control model and related studies,the present paper introduces a variable about individual difference,namely self-efficacy,and proposes the fit model between self-efficacy and job control.Furthermore,this paper confirms this new model with 344 effective questionnaires which are collected from medical organizations,through multiple hierarchical regression.The fit model explains in details how the person with high self-efficacy cope with work stress,and then puts forward the work stress pattern matching the person with low self-efficacy,which expands Karasek's job demands-control model and has certain values in the practice and research.