industry-university-research institute network is characterized by microcosm network,its network structure optimization is helpful to promote innovation.In this paper,with microcosm network model,it focuses on the characteristics of industry-university-research institute network structure,its integration innovation is affected by communication frequency and clustering extent.Based on industry-university-research institute net characteristics,it proposes a series of cultivation strategies that promotes cooperation communication,in order to realize the innovation optimization,better advance commercialization of research findings and promote economic growth.